Analysis Note

ControlHuman trabecular bone in a human bone biopsy.

Application

Detect Osteocalcin using this mouse monoclonal antibody, Anti-Osteocalcin Antibody, Clone 7D1.13 validated for use in IHC (Paraffin) & IHC (tissue).

Research Sub CategoryMesenchymal Stem CellsOsteobiology

General description

Osteocalcin is an abundant, non-collagenous protein component of bone that is produced by osteoblasts. Osteocalcin appears transiently in embryonic bone at the time of mineral deposition, where it binds to hydroxyapatite in a calcium-dependent manner. In addition, osteocalcin is one of the most abundant, non-collagenous proteins found in mineralized adult bone. Osteocalcin is often studied in the osteogenesis of embryonic and mesenchymal stem cells.

Immunogen

KLH-conjugated linear peptide corresponding to Human Osteocalcin.

Linkage

Replaces: MABD182

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Physical form

Format: Purified

Quality

Evaluated by Immunohistochemistry on human trabecular bone in a human bone biopsy.
Immunohistochemical Analysis: A 1:50 Dilution of this antibody detected osteocalcin on human trabecular bone in a human bone biopsy.

Target description

~6 kDa calculated